Autoimmune Neurological Disease by Michael P. Pender

By Michael P. Pender

This booklet presents a complete, up to date and demanding evaluation of the immunological points of autoimmune neurological disorder. those ailments contain universal stipulations akin to a number of sclerosis, the Guillain-Barre syndrome, and myasthenia gravis. The booklet starts with chapters on antigen reputation and self-nonself attractiveness, and neuroimmunology, through chapters on particular ailments. for every ailment, the authors disguise medical gains, genetics, neuropathology, pathophysiology, immunology, and treatment. each one bankruptcy summarizes key issues and indicates instructions for destiny examine. The authors hide animal versions of autoimmune neurological illness intimately due to their value in knowing the human ailments.

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Trends in Neurosciences, 9, 271-7. , Battye, F. W. (1984). Inducible expression of H-2 and la antigens on brain cells. Nature, 310, 688-91. -3Experimental autoimmune encephalomyelitis MICHAEL P. PENDER Introduction Shortly after the introduction of the anti-rabies vaccine by Pasteur in 1885, there appeared reports of neurological complications in some of the patients vaccinated. The complications developed after a latent period and consisted of weakness and sensory disturbance in the limbs, sphincter dysfunction and cranial nerve involvement.

Neuroscience Letters, 85, 317-21. J. W. (1981). Demonstration and characterization of la-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain. Journal of Experimental Medicine, 154, 347-61. N. L. (1987). Microglia are the major cell type expressing MHC class II in human white matter. Journal of the Neurological Sciences, 80,2537. L. & Kimura, H. (1991). T-lymphocyte entry into the central nervous system. Journal of Neuroscience Research, 28, 254—60.

1992). Interactions between CD4+ T-cells and rat Schwann cells in vitro. 1. Antigen presentation by Lewis rat Schwann cells to P2-specific CD4+ T-cell lines. Journal of Neuroimmunology, 40, 1-18. D. & Gatenby, P. (1990). Rat and human Schwann cells in vitro can synthesize and express MHC molecules. Muscle and Nerve, 13, 106-16. F. E. (1977). Immunologically privileged sites. Advances in Immunology, 25, 1-54. C. A. (1989). Expression of MHC antigens in the central nervous system. Transplantation Proceedings, 21, 3163-5.

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