Pain: A Medical and Anthropological Challenge Proceedings of by Prof. Dr. med. Dr. med. h.c. Hans Werner Pia (auth.), Prof.

By Prof. Dr. med. Dr. med. h.c. Hans Werner Pia (auth.), Prof. Dr. Jean Brihaye, Prof. Dr. Fritz Loew, H. W. Pia (eds.)

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Additional info for Pain: A Medical and Anthropological Challenge Proceedings of the First Convention of the Academia Eurasiana Neurochirurgica Bonn, September 25–28, 1985

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1984). Proenkephalin B (also termed prodynorphin) contains three copies of [Leu 5]enkephalin, in addition to a series of larger opioid peptides which have been isolated from the pituitary and brain such as a-neo-endorphin, ~-neo-endorphin, dynorphin A, dynorphin 1-8, dynorphin B (= rimorphin), dynorphin H2~a common precursor for dynorphin A and dynorphin B (Goldstein 1984). Within these precursor molecules the opioid peptide seq uences are flanked by pairs of basic aminoacids (in some cases by only a single basic amino acid) which are known to be sites of attack for proteolytic enzymes (Turner 1984, Fricker 1985) (see Fig.

Adv Physiol Sci, vol 16. Akademiai Kiado, Budapest; Pergamon Press, Oxford, pp 325-333 80. Nadelhaft J, Roppolo J, Morgan C, de Groat WC (1983) Parasympathetic preganglionic neurons and visceral primary afferents in monkey sacral spinal cord revealed following application of horseradish peroxidase to pelvic nerve. J Comp Neurol 216: 36-52 81. Nathan PW (1976) The gate-control theory of pain. A critical review. Brain 99: 123-158 82. Ochoa JL, Torebjork HE (1983) Sensations evoked by intraneural microstimulation of single mechanoreceptor units innervating the human hand.

Guttmann L (1976) Spinal cord injuries. Comprehensive management and research. Blackwell Scientific Publications, Oxford, 2nd ed 38. Hancock MB, Foreman RD, Willis WD (1975) Convergence of visceral and cutaneous input onto spinothalamic tract cells in the thoracic spinal cord of the cat. Exp Neurol 47: 240-248 39. Handwerker HO (1984) Experimentelle Schmerzanalyse beim Menschen. In: Zimmermann M, Handwerker HO (eds) Schmerz. Springer, Berlin Heidelberg New York Tokyo, pp 87123 40. Haupt P, Jiinig W, Kohler W (1983) Response pattern of visceral afferent fibres, supplying colon, upon chemical and mechanical stimuli.

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