Pharmaceutical Manufacturing Encyclopedia by William Andrew Publishing

By William Andrew Publishing

This average encyclopedia on pharmaceutical production techniques has been thoroughly up-to-date to incorporate FDA medicinal drugs licensed as much as the summer season of 2004. The encyclopedia supplies information for the manufacture of 2226 prescription drugs which are being advertised as a trade-named product someplace on this planet. each one access includes:

ò healing functionality
ò Chemical and customary name
ò Structural Formula
ò Chemical Abstracts Registry no.
ò exchange identify, producer, state, and yr introduced
ò uncooked Materials
ò production Process

In addition, references also are stated less than each one drug's access to significant pharmaceutical works the place more information might be bought on synthesis and the pharmacology of the person items.

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After neutralizing with a diluted sodium hydroxide solution, the eluate i s treated with activated charcoal to adsorb ATP as i t s sodium salt, The separated activated charcoal is washed with water and eluted with 60% (volume) ethanol containing 2% (volume) of concentrated aqueous ammonia. 5part by volume, then 5 parts by volume of ethanol is added. 155 part by weight of tetra. sodium salt of ATP containing 4 mols of water of crystallization as a colorless crystalline powder, The yield is 47% relative to the theoretical.

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S. ecetyI-18pglycyrrhetinic acid can be prepared by reaction between 3acetyl18pglycyrrhetinic acid and an aluminum alcoholate. , alcoholates in which the alkoxy group or groups have from one to four carbon atoms. The salification reaction may be carried out a t room temperature or at an elevated temperature in conventional fashion, preferably in the presence of organic solvents. As organic solvents may be used alcohols, ethers, ketones, chlorinated solvents (methylene chloride, chloroform) ethyl acetate, etc.

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